NEW LOOK COMING SOON!
Estro Vitality Oil is a high-potency bioidentical topical oil delivering 0.1mg of USP-grade Estradiol E2 per drop — formulated to support comfort, vitality, and radiant skin health during the menopausal transition.
With a clean, nourishing base of MCT oil and Vitamin E, this lightweight oil absorbs quickly and delivers maximum bioavailability with every use. Up to a 10-month supply at the recommended daily dosage.
How to Use: Apply 2–5 drops to the skin 1–2x daily at recommended sites, ensuring full absorption. Tailor usage to your specific concern — whether menopause support or skin rejuvenation.
- 0.1mg bioidentical E2 per drop
- 1,600 drops per bottle — up to 10-month supply
- Maximum bioavailability
- USP-grade E2
- Free from harmful preservatives
- Made in the USA
Download our FREE Product User Guide Download our Quick Start Guide
Cruelty Free · Fragrance Free · Mineral Oil Free · Paraben Free · Phthalate Free · Silicone Free · Sulfate Free
Disclaimer
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Individual results may vary. Always consult with your healthcare provider before starting any new supplement or skincare product.
Frequently Asked Questions
How can Estro Vitality Oil support me during menopause?
Estro Vitality beauty oil is in a nourishing topical formula. It’s designed to support overall wellness and promote a sense of balance and vitality during perimenopause and post-menopause. Many women find the formula helps maintain emotional well-being, skin hydration, and a sense of energy as their bodies go through natural hormonal changes.
Why choose Estro Vitality Oil over other products?
Estro Vitality Oil is formulated with a clean ingredient profile, free from harmful preservatives. Its smooth, fast-absorbing base makes it easy to apply and use consistently. Each bottle provides up to ten months of use, depending on your personal routine. Crafted for wellness, beauty, and comfort, it’s a favorite among women looking for gentle, supportive daily care.
How do I use Estro Vitality Oil for best results?
Apply 2–5 drops to recommended areas of skin, 1–2 times daily, or as directed by your healthcare provider. With approximately 1,600 drops per bottle, it’s easy to personalize your usage. Many users enjoy incorporating it into a self-care routine focused on skin nourishment and hormonal wellness.





Muriel C. –
I’ll like that you can control the amount.Convenient and absorbs well.
Lauren C. –
Love it!
Katherine M. –
Easy to use!
Lisa –
I am only 1 week into using Estro Vitality oil. So far, no issues with any skin irritation. I will give this product some time to prove its benefits.I will not give a 5 star until I get those kind of results. I use Karen’s progesterone cream and have had no issues.
Lisa A –
I absolutely love the Estradiol Oil. I have Karen’s full
Line up and all of her products are top notch. I use 15 drops 2x daily on my inner arms and the bottle lasted 2.5months.
Jane Chung –
Love it.
Tsipora Borger (verified owner) –
Easily absorbed. And I felt the difference almost immediately. (From using cream previously)
Regina Rittenhouse –
Estro Vitality Pro Oil Drops Arrived quickly. It is easy to apply and feels like it Is mixed in a high quality oil that absorbs quickly. There is a sight graininess that disappears once you rub the oil in and I was expecting that, after reading the short instructions.
Jean Hallman –
Super easy to apply! Lasts a long time and really works!
Kristin Desranleau –
I have been using for approximately 4 weeks. It seems to be alleviating dips.
Nancy A (verified owner) –
I’m 67. I am so grateful for this oil! It’s awesome!
hc –
We trust Karen’s products. Clean and honest
M Stutsman –
I love that these are clean ingredients and absorb quickly.
Catherine Oyster (verified owner) –
I really liked this oil, so simple to use and so few ingredients. Also, with the very low per drop, I didn’t feel worried about using too much if an extra drop or two came out. It also absorbs nice, not gritty. It does say to shake it, which make sure to keep the cap completely twisted closed so no oil spills out! Also, I’m not sure shaking for a long time is necessary. Not sure if it’s a suspension or if it’s more of a mixture, so can’t say for sure. I’m super grateful this is an option. I’m sleeping through the night better, my joints are WAYYYY improved (feel like this is the fastest and first thing I noticed), energy is improving, and I’m feeling much more positive than I have in a long time.