Progest Calm Cream

Rated 4.85 out of 5 based on 61 customer ratings
(61 customer reviews)

Availability: In stock

$59.99

Warning: May cause extreme chill and unbothered fabulousness.

Bioidentical progesterone. Clean formula. Made for this stage of life.

Progest Calm is a topical cosmetic cream formulated with bioidentical USP-grade progesterone, chosen by women during their fertile, perimenopausal, and postmenopausal years as part of a holistic wellness routine.

There comes a point in womanhood where your inner thermostat, patience, sleep, and emotional stability all seem to get together and say: “Let’s keep her guessing.” One week you feel like yourself. The next week you are irritated by the sound of someone breathing too confidently. You may feel wired at night, foggy in the morning, teary over absolutely nothing, and then somehow completely fine again by lunch.

Cute little mystery? Not exactly.

Whether you are still cycling, deep in perimenopause, or on the other side of menopause, hormonal changes can make your body feel less predictable than it used to. And no, you do not need to “just calm down,” which may be the least calming sentence ever spoken.

One small step in your routine. Real comfort. No drama.

Progest Calm is a topical cosmetic cream formulated with USP-grade bioidentical progesterone in a clean, carefully crafted base. Each dose provides 50 mg of bioidentical progesterone in an easy-to-use topical cream.

No fragrance.
No parabens.
No mineral oil.
No “what is even in this?” ingredient list.

Just a simple, high-potency formula intended for external use only.

Why women love it

Many women choose Progest Calm as part of their daily wellness routine to support a greater sense of balance during hormonal transitions. Many users report positive experiences when using progesterone cream.

These may include:

  • A greater sense of calm and emotional balance
  • Improved restfulness and sleep routines
  • A feeling of renewed vitality
  • Skin comfort and tone support
  • Support for a balanced sense of self during hormonal changes

Because sometimes you do not need another lecture about stress management. You need a clean, simple formula that fits into your routine and reminds your body: “We are safe. We are supported. We are not sending that text.”

How to Use

Apply to the inside of forearms, or as directed by your healthcare provider. 50mg progesterone per dose — 70+ day supply.

What’s in it

  • High potency formula
  • USP-grade bioidentical progesterone
  • Free from harmful preservatives
  • Made in the USA in an FDA-inspected facility

Cruelty Free · Fragrance Free · Mineral Oil Free · Paraben Free · Phthalate Free · Silicone Free · Sulfate Free

Download our FREE Product User Guide Download our Quick Start Guide

Disclaimer
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Individual results may vary. Always consult with your healthcare provider before starting any new supplement or skincare product.

Frequently Asked Questions

How can Progest Calm support me during perimenopause or menopause?

Progest Calm is formulated with bioidentical progesterone and is chosen by many women during perimenopause and post-menopause as part of a holistic wellness routine. Many users report a greater sense of calm, improved restfulness, and a balanced sense of self during this stage of life.

As always, consult a qualified healthcare provider to determine if topical progesterone fits your individual needs.

Is Progest Calm safe to use, and how is it different from synthetic hormone options?

Progest Calm uses USP-grade bioidentical progesterone in a clean, fragrance-free base, free from harmful preservatives. As with any new product, talk to your healthcare provider before starting, especially if you’re managing other health conditions or taking other medications.

How do I use Progest Calm, and what can I expect?

Apply to the inside of forearms, or as directed by your healthcare provider. Results vary; many users report feeling a greater sense of calm and steadiness with consistent use.

Weight86 kg
Ingredients

Purified Water
Micronized Progesterone USP
(Wild Yam)
Vegetable Glycerin
Aloe Vera Leaf Gel
Caprylic/Capric Triglyceride
Stearic Acid
Olive Oil
Coconut Oil
Shea Butter
Sunflower Lecithin
Methylsulfonylmethane MSM
Vitamin E
Stearyl Alcohol
Isopropl Palmitate
Allantoin
Carbomer
Sodium Bicarbonate
Herbal-Active (Natural Perservative)
Radish Extract (Natural Perservative)

61 reviews for Progest Calm Cream

  1. Rated 4 out of 5

    Kendra C. (verified owner) –

    The concentration is a little low, so I have to use a lot more of it than compounded formulas to get the dose I need, but I do like the smooth texture and subtle smell of the cream, and I like how it feels.

  2. Rated 5 out of 5

    Lindsay B. –

    I’ve been through two cycles with this and have already noticed a reduction in breast pain before my cycle. It goes on the skin nicely and smells good too!

  3. Rated 5 out of 5

    Phyllis A. (verified owner) –

    Just getting started but seems to be helping my sleep.

  4. Rated 5 out of 5

    abigail c. –

    Thank you! I’m so happy that I was able to start my journey with B-hrt with Karen’s reputable and wonderfully helpful creations!!!!! Thank you so much!!

  5. Rated 5 out of 5

    Diana W. (verified owner) –

    I noticed a difference right away and was able to get a better night’s rest with Progest Calm

  6. Rated 5 out of 5

    Lisa H. –

    Love this cream. Felt a difference within days!!

  7. Rated 5 out of 5

    Shelli O. (verified owner) –

    I love that this progesterone is 50mg vs the average 29mg in other products. Has made a huge difference in my perimenopause journey!

  8. Rated 5 out of 5

    Zora B. –

    I love the progesterone cream. It goes on silky smooth, absorbs well and doesn’t smell. More importantly, it works and doesnt have all the nasties normally made in commercial progesterone creams.

    Highly recommended.

  9. Rated 5 out of 5

    Brenda D. –

    Wonderful cream.

  10. Rated 5 out of 5

    Cindy M. –

    I’ve been using Progest Calm for about six months now. I most definitely can see a difference in my sleep patterns. I’m sleeping more deeply and for longer periods of time without waking. I also don’t wake up in a panic. This is a supplement that is definitely worth adding to my regime.

  11. Rated 4 out of 5

    Kelly S. –

    Arrived quickly, thank you! But I had a lot of trouble getting the product to pump out. I finally turned it upside down and gave it a few hard shakes and it started working.

  12. Rated 5 out of 5

    Katie G. –

    I have been using Progrest Calm for about 3 days now and have noticed a significant difference in my sleep. I wake up well rested! I had a total hysterectomy done about 8 years ago and despite going through surgical menopause, I think I’m going through perimenopause. I like the natural route of things and that’s why I switched from synthetic progesterone to natural. I’ve also lost a pound so far by using Progest Calm!!!

  13. Rated 5 out of 5

    Lindsay B. –

    I have noticed a dramatic decrease in my PMS symptoms. Sore breasts and heavy cramping are dramatically better!

  14. Rated 4 out of 5

    Kerry E. –

    The first bottle of this I bought was rubbing in more nicely. This bottle seems to have some clumps / bumps / texture to it, where it doesn’t rub in seamlessly all the way. :(( I don’t love that inconsistency. But it seems to help me sleep! And you gotta oppose that estrogen, as I am using the estradiol cream also. :)

  15. Rated 5 out of 5

    sandy z. –

    Karen’s progesterone cream is easy to use, in a nice convenient sized bottle.

  16. Rated 5 out of 5

    Kristen U. –

    Love this cream! So happy not to have to take a pill to get the benefit of progesterone!

  17. Rated 5 out of 5

    Jolene C. –

    Noticed an improvement in my anxiety in just a couple of weeks!

  18. Rated 5 out of 5

    Betty A. –

    The Progest Calm is a light cream that absorbs completely and rapidly. It works! My symptoms have improved dramatically. It is a great product!

  19. Rated 3 out of 5

    Alessia S. –

    I’m using it with the cream Estro Rejuvenate which I like so far.

  20. Rated 5 out of 5

    Betty A. –

    Rapidly absorbs, non-greasy. I’m sleeping great and my achy joints are history!

  21. Rated 5 out of 5

    Kristina T. –

    Great product!

  22. Rated 5 out of 5

    Kelly S. –

    I love this cream! I sleep better and feel so much better while using it.

  23. Rated 5 out of 5

    Julianne A. –

    I like the pump, easy application. Been applying Estro, just started progesterone, it is calming. Enjoying this lovely product.

  24. Rated 5 out of 5

    Julia M. –

    Wonderful addition to my 100 mg of oral progesterone which I use at night. The cream feels very good on the skin and it helps me to sleep through the night, when I have to take my break from it, I miss it! thank you very much for making this product that works so well and knowing that it’s bioidentical brings peace to my mind. Thank you from the bottom of my heart and please don’t stop making these beautiful creams.

  25. Rated 5 out of 5

    Maria P. –

    Works great so far!

  26. Rated 5 out of 5

    Amanda W. –

    Love it

  27. Rated 5 out of 5

    Lori F. (verified owner) –

    Definitely helps me fall asleep again when I wake during the night. Tremendously better sleep when using this cream.

  28. Rated 5 out of 5

    Melissa C. –

    This is my second Progesterone cream purchase from Karen Martel. I had my hormones checked but my Dr said my labs showed normal for everything. At 49 and lots of symptoms I went on a journey to find a solution. I saw Dr Lisa Weidmen( carnivore Doctor) posted something about these creams It has helped tremendously with feeling less anxious , more sound sleep & regulating my cycle. I also use the Estrogen Vitality! I try to use it as cyclical every month.

  29. Rated 3 out of 5

    stacy c. –

    I have had no change yet

  30. Rated 5 out of 5

    Kristen U. –

    After switching from a progesterone pill to Karen’s topical progesterone I no longer spot my nights are more peaceful. I love that my liver doesn’t have to process it! When Karen explained that on her podcast it made so much sense! I leave my bottle by my bedside and apply it on my thighs before climbing in. Honestly after finding Karen Martel my life has changed in so many empowering ways.

  31. Rated 5 out of 5

    sandy z. –

    The cream is just the right consistency to blend well when you apply it. One container lasts quite a while!

  32. Rated 5 out of 5

    Jennifer H. –

    I am sleeping better and yes, feeling more calm !

  33. Rated 5 out of 5

    Barbara A. –

    Great product – it definitely helps with symptoms!

  34. Rated 5 out of 5

    Alyssa M. –

    I’m not sleeping as deep as I want, but this has helped! I might need more of a slather than the average person lol, but it HELPS!

  35. Rated 5 out of 5

    Teresa L. –

    Absorbs quickly and isn’t a massive quantity. I love knowing that each pump equals 50mg, rather than “eyeballing” it. My last progesterone cream was 1 teaspoon dosage and it took forever to rub in adequately. I have been on 600mg of oral progesterone and this did nothing to change my blood test values. This cream, from Karen Martel, changed them.

  36. Rated 5 out of 5

    Cyn H. –

    As soon as I started using Progest Calm I slept more soundly and woke up feeling more rested. I feel protected using this while using the Estrogen cream too.

  37. Rated 5 out of 5

    sandy z. –

    Karen’s progesterone cream is easy to use and it absorbs quickly without being greasy or tacky. Thank you for having great products!

  38. Rated 5 out of 5

    Susan S. –

    Excellent.

  39. Rated 3 out of 5

    Rebecca B. –

    I’m not sure if the estradiol and progesterone is helping.

  40. Rated 5 out of 5

    Lori R. –

    I have been suffering for awhile this worked for me immediately! I would recommend this product to other women going through their menopause journey. THANK YOU for creating this beautiful cream.

    Lori R from Alabama

  41. Rated 5 out of 5

    Cindy M. –

    I have been using Progest Calm for about six months now, and I can attest to the fact that I’m resting better at night. I feel good about using something safe that isn’t just another pill, too. Wonderful product!

  42. Rated 5 out of 5

    rita m. –

    Love using this progesterone in combination with my oral progesterone. It helps my sleep and my markers are better!

  43. Rated 5 out of 5

    Laurie S. (verified owner) –

    I wear a Garmin watch which monitors my sleep and since taking the progesterone cream I have seen a marked improvement in my sleep.

  44. Rated 5 out of 5

    Connie –

    TUSTIN, CALIFORNIA, UNITED STATES

    So far, so good. Waiting for results as I’ve only used it for 1 week. However, the packaging is beautiful!!

  45. Rated 5 out of 5

    Amanda Hahn –

    STEVENSVILLE, MARYLAND, UNITED STATES

    Great product. It’s light and clean feeling. I use it before bed and it feel like it’s helping to balance my use of the estrogen cream.

  46. Rated 5 out of 5

    christina Lockwood (verified owner) –

    BONITA SPRINGS, FLORIDA, UNITED STATES

    I am pretty new to bhrt and feel so comfortable with Karen’s products. The cream feels so good and I am sleeping better at night. Looking forward to running my labs so see where my levels are. Feeling a difference in such a great way!!! Love this product!

  47. Rated 5 out of 5

    Donna Jordan (verified owner) –

    JEWETT CITY, CONNECTICUT, UNITED STATES

    Love progest calm. I’m sleeping through the night finally

  48. Rated 5 out of 5

    Sarah T (verified owner) –

    LEXINGTON, SOUTH CAROLINA, UNITED STATES

    This really helped me to sleep better and feel more energized the next day. I also had fewer PMS symptoms. I highly recommend this product!

  49. Rated 5 out of 5

    Zsuzsa Kimball –

    MEDFORD, MASSACHUSETTS, UNITED STATES

    Really like this cream! It spreads nicely and I can see my sleep is better on my Fitbit. Thank you for making this cream available.

  50. Rated 5 out of 5

    Sherilyn Johnson –

    MARIETTA, GEORGIA, UNITED STATES

    Knowing that progesterone is one of the first hormones to decline, I began using the Progest Calm to support my sleep and anxiety. I am always a little sad when I have to stop using it for the recommended amount of time and feel so much more peaceful during the time of the month I use it.

  51. Rated 5 out of 5

    Nancy Watkins –

    DENVER, COLORADO, UNITED STATES

    It is a great product! It has helped with my sleep and the skin on my chest where I apply it is softer and smoother!

  52. Rated 5 out of 5

    Chelsea –

    ALLENTOWN, PENNSYLVANIA, UNITED STATES

    I love this product it has changed my life!!

  53. Rated 5 out of 5

    Brittany Higley (verified owner) –

    SEATTLE, WASHINGTON, UNITED STATES

    I am so happy with ProgestCalm. Thank goodness for the progesterone and the good clean ingredients. This always helps me in my luteal phase. Just wonderful.

  54. Rated 5 out of 5

    Sherrie Hursh (verified owner) –

    ATMORE, ALABAMA, UNITED STATES

    This has taken my night sweats away. It has also helped me to sleep more soundly and deeply. Don’t leave home without it!!

  55. Rated 5 out of 5

    Diane Hendricks –

    ASHBURN, VIRGINIA, UNITED STATES

    Love the Progesterone cream. The easy pump and new bottles are so easy to use. Gives me just the right amount for my body.

  56. Rated 5 out of 5

    Catherine Oyster (verified owner) –


    Let us know what you think! :

    I found this cream to be very calming, and I like the dispenser as well. It is easy to know how many pumps you are using, and it wasn’t an excessive amount of cream like I’ve experienced with some other OTC brands. Easy to put on and let it absorb quickly.

  57. Rated 5 out of 5

    Sherliyn J. –


    Let us know what you think! :

    Knowing that progesterone is one of the first hormones to decline, I began using the Progest Calm to support my sleep and anxiety. I am always a little sad when I have to stop using it for the recommended amount of time and feel so much more peaceful during the time of the month I use it.

  58. Rated 5 out of 5

    Peggy F. (verified owner) –

    I am feeling better and healthier.

  59. Rated 5 out of 5

    Dana A. (verified owner) –

    This is my first month using the Progest Calm cream. I put it on before bed. I seem to have consist full night sleeps since starting this product. I will continue for a few more months to see if this continues.

  60. Rated 5 out of 5

    TERRIE (verified owner) –

    Amazing cream! Loving it.

  61. Rated 5 out of 5

    Annah Gardner (verified owner) –

    Easy to apply.

Only logged in customers who have purchased this product may leave a review.

What Women Are Saying About Our Products

Frequently Asked Questions

We recommend consulting a qualified healthcare provider before starting any new hormone-containing cosmetic, especially if you have a personal or family history of hormone-sensitive conditions.

Because every woman’s hormone journey is different, we recommend starting with our hormone quiz to help identify the products best suited to your symptoms and wellness goals.

It varies. Some customers notice their skin looks and feels different within days. Others find the changes become more visible over several weeks. Most reviews mention a noticeable difference within the first month.

No our products are not prescription based formulas. They are OTC cosmetic creams and oils that contain USP grade hormones. We do offer prescription medications through our third party medical providers. If you are interested please contact [email protected].

Standard shipping within the U.S. typically takes 7–10 business days. Delivery times may vary depending on location and seasonal demand.

At this time, international shipping is not available, though the company is working toward offering it in the future.

Once your order ships, you’ll receive a confirmation email containing your tracking number and tracking link.

Returns are accepted on unopened products within 15–30 days of purchase, depending on the item and condition. Products must be unused and in their original packaging. Digital products and accessed online programs are non-refundable.

Yes. Most memberships and subscriptions can be self-managed and canceled directly through your account dashboard.

You can log into your account, navigate to the subscription section, and update products, skip shipments, change billing details, or cancel your subscription.

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