Progest Calm is a topical cosmetic cream formulated with USP-grade bioidentical progesterone in a clean, carefully crafted base. Each dose provides 50 mg of bioidentical progesterone in an easy-to-use topical cream.
No fragrance.
No parabens.
No mineral oil.
No “what is even in this?” ingredient list.
Just a simple, high-potency formula intended for external use only.
Why women love it
Many women choose Progest Calm as part of their daily wellness routine to support a greater sense of balance during hormonal transitions. Many users report positive experiences when using progesterone cream.
These may include:
- A greater sense of calm and emotional balance
- Improved restfulness and sleep routines
- A feeling of renewed vitality
- Skin comfort and tone support
- Support for a balanced sense of self during hormonal changes
Because sometimes you do not need another lecture about stress management. You need a clean, simple formula that fits into your routine and reminds your body: “We are safe. We are supported. We are not sending that text.”
How to Use
Apply to the inside of forearms, or as directed by your healthcare provider. 50mg progesterone per dose — 70+ day supply.
What’s in it
- High potency formula
- USP-grade bioidentical progesterone
- Free from harmful preservatives
- Made in the USA in an FDA-inspected facility
Cruelty Free · Fragrance Free · Mineral Oil Free · Paraben Free · Phthalate Free · Silicone Free · Sulfate Free
Download our FREE Product User Guide Download our Quick Start Guide
Disclaimer
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Individual results may vary. Always consult with your healthcare provider before starting any new supplement or skincare product.
Frequently Asked Questions
How can Progest Calm support me during perimenopause or menopause?
Progest Calm is formulated with bioidentical progesterone and is chosen by many women during perimenopause and post-menopause as part of a holistic wellness routine. Many users report a greater sense of calm, improved restfulness, and a balanced sense of self during this stage of life.
As always, consult a qualified healthcare provider to determine if topical progesterone fits your individual needs.
Is Progest Calm safe to use, and how is it different from synthetic hormone options?
Progest Calm uses USP-grade bioidentical progesterone in a clean, fragrance-free base, free from harmful preservatives. As with any new product, talk to your healthcare provider before starting, especially if you’re managing other health conditions or taking other medications.
How do I use Progest Calm, and what can I expect?
Apply to the inside of forearms, or as directed by your healthcare provider. Results vary; many users report feeling a greater sense of calm and steadiness with consistent use.





Kendra C. (verified owner) –
The concentration is a little low, so I have to use a lot more of it than compounded formulas to get the dose I need, but I do like the smooth texture and subtle smell of the cream, and I like how it feels.
Lindsay B. –
I’ve been through two cycles with this and have already noticed a reduction in breast pain before my cycle. It goes on the skin nicely and smells good too!
Phyllis A. (verified owner) –
Just getting started but seems to be helping my sleep.
abigail c. –
Thank you! I’m so happy that I was able to start my journey with B-hrt with Karen’s reputable and wonderfully helpful creations!!!!! Thank you so much!!
Diana W. (verified owner) –
I noticed a difference right away and was able to get a better night’s rest with Progest Calm
Lisa H. –
Love this cream. Felt a difference within days!!
Shelli O. (verified owner) –
I love that this progesterone is 50mg vs the average 29mg in other products. Has made a huge difference in my perimenopause journey!
Zora B. –
I love the progesterone cream. It goes on silky smooth, absorbs well and doesn’t smell. More importantly, it works and doesnt have all the nasties normally made in commercial progesterone creams.
Highly recommended.
Brenda D. –
Wonderful cream.
Cindy M. –
I’ve been using Progest Calm for about six months now. I most definitely can see a difference in my sleep patterns. I’m sleeping more deeply and for longer periods of time without waking. I also don’t wake up in a panic. This is a supplement that is definitely worth adding to my regime.
Kelly S. –
Arrived quickly, thank you! But I had a lot of trouble getting the product to pump out. I finally turned it upside down and gave it a few hard shakes and it started working.
Katie G. –
I have been using Progrest Calm for about 3 days now and have noticed a significant difference in my sleep. I wake up well rested! I had a total hysterectomy done about 8 years ago and despite going through surgical menopause, I think I’m going through perimenopause. I like the natural route of things and that’s why I switched from synthetic progesterone to natural. I’ve also lost a pound so far by using Progest Calm!!!
Lindsay B. –
I have noticed a dramatic decrease in my PMS symptoms. Sore breasts and heavy cramping are dramatically better!
Kerry E. –
The first bottle of this I bought was rubbing in more nicely. This bottle seems to have some clumps / bumps / texture to it, where it doesn’t rub in seamlessly all the way. :(( I don’t love that inconsistency. But it seems to help me sleep! And you gotta oppose that estrogen, as I am using the estradiol cream also. :)
sandy z. –
Karen’s progesterone cream is easy to use, in a nice convenient sized bottle.
Kristen U. –
Love this cream! So happy not to have to take a pill to get the benefit of progesterone!
Jolene C. –
Noticed an improvement in my anxiety in just a couple of weeks!
Betty A. –
The Progest Calm is a light cream that absorbs completely and rapidly. It works! My symptoms have improved dramatically. It is a great product!
Alessia S. –
I’m using it with the cream Estro Rejuvenate which I like so far.
Betty A. –
Rapidly absorbs, non-greasy. I’m sleeping great and my achy joints are history!
Kristina T. –
Great product!
Kelly S. –
I love this cream! I sleep better and feel so much better while using it.
Julianne A. –
I like the pump, easy application. Been applying Estro, just started progesterone, it is calming. Enjoying this lovely product.
Julia M. –
Wonderful addition to my 100 mg of oral progesterone which I use at night. The cream feels very good on the skin and it helps me to sleep through the night, when I have to take my break from it, I miss it! thank you very much for making this product that works so well and knowing that it’s bioidentical brings peace to my mind. Thank you from the bottom of my heart and please don’t stop making these beautiful creams.
Maria P. –
Works great so far!
Amanda W. –
Love it
Lori F. (verified owner) –
Definitely helps me fall asleep again when I wake during the night. Tremendously better sleep when using this cream.
Melissa C. –
This is my second Progesterone cream purchase from Karen Martel. I had my hormones checked but my Dr said my labs showed normal for everything. At 49 and lots of symptoms I went on a journey to find a solution. I saw Dr Lisa Weidmen( carnivore Doctor) posted something about these creams It has helped tremendously with feeling less anxious , more sound sleep & regulating my cycle. I also use the Estrogen Vitality! I try to use it as cyclical every month.
stacy c. –
I have had no change yet
Kristen U. –
After switching from a progesterone pill to Karen’s topical progesterone I no longer spot my nights are more peaceful. I love that my liver doesn’t have to process it! When Karen explained that on her podcast it made so much sense! I leave my bottle by my bedside and apply it on my thighs before climbing in. Honestly after finding Karen Martel my life has changed in so many empowering ways.
sandy z. –
The cream is just the right consistency to blend well when you apply it. One container lasts quite a while!
Jennifer H. –
I am sleeping better and yes, feeling more calm !
Barbara A. –
Great product – it definitely helps with symptoms!
Alyssa M. –
I’m not sleeping as deep as I want, but this has helped! I might need more of a slather than the average person lol, but it HELPS!
Teresa L. –
Absorbs quickly and isn’t a massive quantity. I love knowing that each pump equals 50mg, rather than “eyeballing” it. My last progesterone cream was 1 teaspoon dosage and it took forever to rub in adequately. I have been on 600mg of oral progesterone and this did nothing to change my blood test values. This cream, from Karen Martel, changed them.
Cyn H. –
As soon as I started using Progest Calm I slept more soundly and woke up feeling more rested. I feel protected using this while using the Estrogen cream too.
sandy z. –
Karen’s progesterone cream is easy to use and it absorbs quickly without being greasy or tacky. Thank you for having great products!
Susan S. –
Excellent.
Rebecca B. –
I’m not sure if the estradiol and progesterone is helping.
Lori R. –
I have been suffering for awhile this worked for me immediately! I would recommend this product to other women going through their menopause journey. THANK YOU for creating this beautiful cream.
Lori R from Alabama
Cindy M. –
I have been using Progest Calm for about six months now, and I can attest to the fact that I’m resting better at night. I feel good about using something safe that isn’t just another pill, too. Wonderful product!
rita m. –
Love using this progesterone in combination with my oral progesterone. It helps my sleep and my markers are better!
Laurie S. (verified owner) –
I wear a Garmin watch which monitors my sleep and since taking the progesterone cream I have seen a marked improvement in my sleep.
Connie –
So far, so good. Waiting for results as I’ve only used it for 1 week. However, the packaging is beautiful!!
Amanda Hahn –
Great product. It’s light and clean feeling. I use it before bed and it feel like it’s helping to balance my use of the estrogen cream.
christina Lockwood (verified owner) –
I am pretty new to bhrt and feel so comfortable with Karen’s products. The cream feels so good and I am sleeping better at night. Looking forward to running my labs so see where my levels are. Feeling a difference in such a great way!!! Love this product!
Donna Jordan (verified owner) –
Love progest calm. I’m sleeping through the night finally
Sarah T (verified owner) –
This really helped me to sleep better and feel more energized the next day. I also had fewer PMS symptoms. I highly recommend this product!
Zsuzsa Kimball –
Really like this cream! It spreads nicely and I can see my sleep is better on my Fitbit. Thank you for making this cream available.
Sherilyn Johnson –
Knowing that progesterone is one of the first hormones to decline, I began using the Progest Calm to support my sleep and anxiety. I am always a little sad when I have to stop using it for the recommended amount of time and feel so much more peaceful during the time of the month I use it.
Nancy Watkins –
It is a great product! It has helped with my sleep and the skin on my chest where I apply it is softer and smoother!
Chelsea –
I love this product it has changed my life!!
Brittany Higley (verified owner) –
I am so happy with ProgestCalm. Thank goodness for the progesterone and the good clean ingredients. This always helps me in my luteal phase. Just wonderful.
Sherrie Hursh (verified owner) –
This has taken my night sweats away. It has also helped me to sleep more soundly and deeply. Don’t leave home without it!!
Diane Hendricks –
Love the Progesterone cream. The easy pump and new bottles are so easy to use. Gives me just the right amount for my body.
Catherine Oyster (verified owner) –
I found this cream to be very calming, and I like the dispenser as well. It is easy to know how many pumps you are using, and it wasn’t an excessive amount of cream like I’ve experienced with some other OTC brands. Easy to put on and let it absorb quickly.
Sherliyn J. –
Knowing that progesterone is one of the first hormones to decline, I began using the Progest Calm to support my sleep and anxiety. I am always a little sad when I have to stop using it for the recommended amount of time and feel so much more peaceful during the time of the month I use it.
Peggy F. (verified owner) –
I am feeling better and healthier.
Dana A. (verified owner) –
This is my first month using the Progest Calm cream. I put it on before bed. I seem to have consist full night sleeps since starting this product. I will continue for a few more months to see if this continues.
TERRIE (verified owner) –
Amazing cream! Loving it.
Annah Gardner (verified owner) –
Easy to apply.